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High-dose oncogenic PIK3CA drives constitutive cellular stemness through self-sustained TGFβ pathway activation
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Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x.
Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
Elife. 2019 May 24;8. pii: e44635. doi: 10.7554/eLife.44635.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion
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Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.
PLoS Biology 2019 Mar 21;17(3):e2006540. doi: 10.1371/journal.pbio.2006540.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Farnesylated heat shock protein 40 is a component of membrane-bound RISC in Arabidopsis.
J Biol Chem. 2018 Oct 26;293(43):16608-16622. doi: 10.1074/jbc.RA118.003887.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Deep Neural Networks Identify Signaling Mechanisms of ErbB-Family Drug Resistance From a Continuous Cell Morphology State Space
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Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Bowhead: Bayesian modelling of cell velocity during concerted cell migration.
PLoS Comput Biol. 2018 Jan 8;14(1):e1005900. doi: 10.1371/journal.pcbi.1005900.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments
Cell Reports 2017 Sep 19;20(12):2784-2791. doi: 10.1016/j.celrep.2017.08.095.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Pathway and network analysis of cancer genomes.
Nature Methods. 2015 Jun 30;12(7):615-21.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]