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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.
PLoS Biology 2019 Mar 21;17(3):e2006540. doi: 10.1371/journal.pbio.2006540.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
Elife. 2019 May 24;8. pii: e44635. doi: 10.7554/eLife.44635.
Located in Publications / Linding Lab, BRIC & DTU [2011-2018]
Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x.
Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion
PREPRINT
Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
High-dose oncogenic PIK3CA drives constitutive cellular stemness through self-sustained TGFβ pathway activation
PREPRINT
Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
Deep Neural Networks Identify Signaling Mechanisms of ErbB-Family Drug Resistance From a Continuous Cell Morphology State Space
PREPRINT
Located in Publications / Linding Lab, REWIRE, HUB [2019-present]
PhD thesis (Rune Linding)
EMBL April 2004.
Located in Publications / Rune Linding, EMBL [work from 2000-2004]
Cell-Specific Information Processing in Segregating Cell Populations
In this Research Article published in Science, we provide the first systems- and cell-specific network models of contact-initiated signaling between two distinct cell types.
Located in News
Systematic discovery of in vivo phosphorylation networks.
Cell. 2007 Jun 29;129(7):1415-26. Epub 2007 Jun 14.
Located in Publications / Dr Linding, SLRI & MIT [work from 2005-2007]
NetworKIN: a resource for exploring cellular phosphorylation networks.
Nucleic Acids Res. 2008 Jan;36(Database issue):D695-9. Epub 2007 Nov 2.
Located in Publications / Dr Linding, SLRI & MIT [work from 2005-2007]