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Computational approaches to identify functional genetic variants in cancer genomes.
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Nature Methods 2013 Jul 30;10(8):723-9.
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Linding Lab, BRIC & DTU [2011-2018]
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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling.
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Cell. 2015 Sep 16. pii: S0092-8674(15)01108-3. doi: 10.1016/j.cell.2015.08.056.
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Linding Lab, BRIC & DTU [2011-2018]
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Unmasking Determinants of Specificity in the Human Kinome.
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Cell. 2015 Sep 16. pii: S0092-8674(15)01109-5. doi: 10.1016/j.cell.2015.08.057.
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Linding Lab, BRIC & DTU [2011-2018]
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Cancer systems biology: Harnessing off-target effects.
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Nature Chemical Biology 2017 Nov 21;13(12):1204-1205. doi: 10.1038/nchembio.2519.
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Linding Lab, BRIC & DTU [2011-2018]
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Bowhead: Bayesian modelling of cell velocity during concerted cell migration.
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PLoS Comput Biol. 2018 Jan 8;14(1):e1005900. doi: 10.1371/journal.pcbi.1005900.
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Linding Lab, BRIC & DTU [2011-2018]
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Farnesylated heat shock protein 40 is a component of membrane-bound RISC in Arabidopsis.
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J Biol Chem. 2018 Oct 26;293(43):16608-16622. doi: 10.1074/jbc.RA118.003887.
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Linding Lab, BRIC & DTU [2011-2018]
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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.
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PLoS Biology 2019 Mar 21;17(3):e2006540. doi: 10.1371/journal.pbio.2006540.
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Linding Lab, BRIC & DTU [2011-2018]
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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
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Elife. 2019 May 24;8. pii: e44635. doi: 10.7554/eLife.44635.
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Linding Lab, BRIC & DTU [2011-2018]
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Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments
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Cell Reports 2017 Sep 19;20(12):2784-2791. doi: 10.1016/j.celrep.2017.08.095.
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Linding Lab, BRIC & DTU [2011-2018]