Selected Publications
Collection of selected publications
- Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin–Expressing Cells.
- Science. 2009 Dec 11;326(5959):1502-9.
- Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells
- Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer treatments.
- Protein disorder prediction: implications for structural proteomics.
- Structure. 2003 Nov;11(11):1453-9.
- Systematic discovery of new recognition peptides mediating protein interaction networks.
- PLoS Biol. 2005 Dec;3(12):e405. Epub 2005 Nov 15.
- ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
- Nucleic Acids Res. 2003 Jul 1;31(13):3625-30.
- GlobPlot: Exploring protein sequences for globularity and disorder.
- Nucleic Acids Res. 2003 Jul 1;31(13):3701-8.
- Synthetic modular systems - reverse engineering of signal transduction.
- FEBS Lett. 2005 Mar 21;579(8):1808-14.
- Navigating cancer network attractors for tumor-specific therapy
- Nature Biotechnology 30, 842–848 (2012)
- Cells, shared memory and breaking the PTM code
- Molecular Systems Biology 8 Article number: 598 doi:10.1038/msb.2012.33
- Network Medicine Strikes a Blow against Breast Cancer
- Cell. 2012 May 11;149(4):731-3.
- Response to Comment on “Positive Selection of Tyrosine Loss in Metazoan Evolution”
- Science 20 May 2011: Vol. 332 no. 6032 p. 917
- Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling.
- Cell. 2015 Sep 16. pii: S0092-8674(15)01108-3. doi: 10.1016/j.cell.2015.08.056.
- Unmasking Determinants of Specificity in the Human Kinome.
- Cell. 2015 Sep 16. pii: S0092-8674(15)01109-5. doi: 10.1016/j.cell.2015.08.057.
- Bowhead: Bayesian modelling of cell velocity during concerted cell migration.
- PLoS Comput Biol. 2018 Jan 8;14(1):e1005900. doi: 10.1371/journal.pcbi.1005900.
- Farnesylated heat shock protein 40 is a component of membrane-bound RISC in Arabidopsis.
- J Biol Chem. 2018 Oct 26;293(43):16608-16622. doi: 10.1074/jbc.RA118.003887.
- Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.
- PLoS Biology 2019 Mar 21;17(3):e2006540. doi: 10.1371/journal.pbio.2006540.
- Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs.
- Elife. 2019 May 24;8. pii: e44635. doi: 10.7554/eLife.44635.
- Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
- Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x.
- Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion
- PREPRINT
- High-dose oncogenic PIK3CA drives constitutive cellular stemness through self-sustained TGFβ pathway activation
- PREPRINT